The fastest enzyme engineering technology with the deepest enzyme database

"Allozymes' revolutionary platform combines advanced computational design,
ultra-high-throughput microfluidics, and machine learning to rapidly screen millions of enzyme variants and identify those with desired functions.

This technology, with over 99% accuracy, accelerates enzyme discovery and engineering by 10x, bringing innovative biosolutions to market faster.

Microfluidics & Ultra High-Throughput Screening

At the heart of our technology lies our proprietary microfluidic platform enables ultra-high-throughput screening, allowing us to analyze millions of enzyme variants simultaneously.

This revolutionary approach accelerates enzyme discovery and optimization, bringing innovative biosolutions to market faster.

What is microfluidics?

Microfluidics involves manipulating tiny volumes of fluids in channels with dimensions on the order of micrometers.

  • Proprietary Chip Designs

    Various chip designs for complex screening workflows.

  • Proprietary Droplet Sorter

    Proprietary sorting unit for droplet sorting.

  • Post-Sorting Automation

    Droplets are automatically sorted and collected for further analysis.

  • Generic DetectionAssays

    Covering several classes of enzymes with generic and sensitive assays.

Data & AI

We are building a comprehensive enzyme database, one of the largest in the world. This data, combined with powerful machine learning algorithms, empowers us to predict novel enzyme functions and engineer enzymes with specific properties.

Genetically encoded

  • Protein

    20 naturally occurring amino acids.

  • Combinatorial Potential

    Trillions of combinations of a 10-amino acid peptide.

  • The Allozymes Approach

    Combines predictive tools with ultra-high-throughput methods. Testing the most promising enzyme combinations.

Directed evolution

  1. Screening Data or Protein Modelling

    Generate data to drive protein modelling strategies.

  2. Build Diverse Libraries

    Create multiple libraries to explore enzyme activity landscape.

  3. Test and Assess Fitness

    Quickly test enzymes for functionality and fitness.

  4. Select Best Enzymes

    Identify and select top-performing enzymes.

Scaling Up with Bioprocess Design

Our unique approach to help companies seamlessly scale-up their bioproducts for crucial steps like regulatory testing, or even early commercial launches.

  1. 1.5 L & 14 L Trials

    Using 1.5 L bioreactors for precise bioprocess optimization and 14 L fermenters for pre-pilot scale-up to transform scientific insights into scalable solutions ready for real-world impact.

  2. 150 L Piloting

    A crucial step in converting lab-born ideas into industrial-scale operations.

  3. Cell Lysis / Separation

    Breaking open cells to release their internal contents and remove debris and unwanted components from the lysate through methods like centrifugation or filtration.

  4. Product Concentration

    Concentrating and enriching the target product using techniques like ultrafiltration or precipitation.

  5. Chromatography

    Purifying the target product based on its properties, such as size, charge, or affinity, using chromatographic columns.

  6. Drying

    Removing moisture from the purified product, typically through freeze-drying or spray drying or vacuum drying, to ensure stability and shelf life.

Picture of our 150 L bioreactor

We use our 150 L bioreactor which allows us to produce the product in a controlled environment. This is perfect for pilot-scale production.